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| Produkte: |
| AGE |
| BioPrime Antikörper |
| BioPrime Färbereagenzien |
| BioPrime Zubehör |
| ECM |
| ELISA |
| Enzyme |
| Forschung |
| Proteine & Peptide |
| VECTOR Reagenzien |
Preis: 480 € / 50 µl
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| Präsentation: | Originalserum lyophilisiert |
| Immunogen: | Synthetisches humanes VIP (Peninsula) |
| Spezifität: | VIP, Vasoaktives Intestinales Polypeptid, keine Kreuzreaktion mit PHI |
| Artspezifität: | Mensch, Schaf, Schwein und andere Vertebraten |
| Allgemeines: | Vasoactive intestinal peptide (VIP) is a 28-amino-acid neuropeptide hormone. Its sequence is identical in man, ox, pig and rat. VIP is widely distributed in the central and peripheral nervous systems, acting as a neurotransmitter or neuromodulator. Peripherally it is involved in vaso- and bronchodilatation, smooth muscle relaxation and stimulation of secretion. Ectopic endocrine tumours secreting VIP (VIPomas) give rise to raised plasma levels of VIP and are associated with watery diarrhoea, hypokaliemia and achlorhydria syndrome. VIP shows high sequence homology with peptide histidine-methionine (PHM) in humans and peptide histidine-serine (PHI) in pig or rat and is exprimed in the same precursor. |
| Positivkontrolle: | Small intestine, ileum (preferably Stefanini-fixed |
| Vorbehandlung: | Pre-treatment of paraffin material is not required, but enhanced staining may occur after application of high temperature unmasking (method not established). |
| Anwendung: | IHC(C, P) |
| Inkubationszeit: | 60 min at RT or 18 hr at 4 degrees C |
| Sekundärreagenzien: | We recommend the use of a specific anti guinea pig IgG conjugate e.g. goat-anti-guinea pig IgG:Biotin (VECTOR Art. no. BA-7000). |
| Lagerung: | -20'°C' |
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